Morpheus

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=== Module 0: Introduction ===

Author: Lutz Brusch

Aim:
  * Define relation between experiment and theory, bottom-up versus top-down models
  * See model as tool, get to know a success story

Description:
  * Discuss previous experiences by students with models
  * Ask expectations, explain schedule of week, day, when hands-on parts 
  * Present slides
  * including
  - top-down success story [Herrgen et al. 2010]
  - Comparison of concepts
  - Model: model organism (model of human physiology) versus conceptual model (end of paper, static representation, flowchart) versus mathematical models (typically: dynamical system theory)
  - for mathematical models: analytical solution (extra insight) versus simulation, choose adequate model formalism, discrete versus continuous, deterministic versus stochastic, single-cell versus multicellular, bottom-up versus top-down
  - Historical overview of pattern formation

Documents:
  * {{:documentation:digs-bb_practical_introduction.pptx|Slides (pptx)}} 
 
Paper:
  * Herrgen, L., Ares, S., Morelli, L.G., Schröter, C., Jülicher, F., and Oates, A.C. (2010) Intercellular Coupling Regulates the Period of the Segmentation Clock. Curr. Biol. 20(14):1244-1253. PMID 20637620. [[http://dx.doi.org/10.1016/j.cub.2010.06.034|link]]