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--- documentation:course:module5 [14:35 14.12.2012] – Page moved from documentation:module5 to documentation:course:module5 Walter
+++ documentation:course:module5 [10:55 11.11.2013] (current) – Walter
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-=== Module 5: Placeholder ===
+=== Module 5: Cell fate decisions (model assumptions) ===
 Author: Name
 Aim:
-  * Main scientific goal
+  * Learn to make implicit model assumptions explicit
-  * Didactive aim
+  * Learn about effect of noise and motility on cell fate decisions
 Description:
-  * Step by step description of module
+  * Introduce Delta-Notch model and patterning
-  * Written such that other tutors can teach the same stuff
+      * dXi/dt = t/(t+aXj) - Xi + eta
+      * Spatial patterning: checkerboard
+  * Assignment 1:
+      *
+  * Introduce tau
+      * Time to decision (tau) depends on noise amplitude
+      * Tau is important in context of other timed processes (e.g. lateral stabilization)
+  *
 Paper:
-  * Wolpert L (1969). "Positional information and the spatial pattern of cellular differentiation". J. Theor. Biol. 25 (1): 1–47. doi:10.1016/S0022-5193(69)80016-0. PMID 4390734. [[http://dx.doi.org/10.1016/S0022-5193(69)80016-0|link]]
+  * de Back W, Zhou JX, Brusch L. 2012, On the role of lateral stabilization during early patterning in the pancreas. J R Soc Interface 10: 20120766. [[http://dx.doi.org/10.1098/rsif.2012.0766|link]] {{:course:pancreaspatterning_jrsocinterface2012.pdf|pdf}}
+  * W. de Back, R. Zimm, L. Brusch 2013, Transdifferentiation of Pancreatic Cells by Loss of Contact-mediated Signaling. BMC Systems Biology 7:77. [[http://www.biomedcentral.com/1752-0509/7/77|link]]
+Documents:
+  *
 Morpheus models:
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