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        <title>Morpheus</title>
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        <title>documentation:documentation</title>
        <link>https://imc.zih.tu-dresden.de/wiki/morpheus/doku.php?id=documentation:documentation&amp;rev=1386620234</link>
        <description>Documentation

User Manual

The user manual is the central resource for up-to-date information on:

	*  graphical user interface and workflow tools
	*  modeling formalisms and numerical implementation
	*  model description language 
	*  model integration and simulation schedule</description>
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        <description>Frequently asked questions

General

More details

 More information 

For more information, refer to the user manual.

Modeling

Random seed

 Random seed 

	*  Mersenne Twister from C\+\+ compiler (gcc version &gt; 4.6) or Boost library when available.
	*  Time $Latex$$Latex$</description>
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        <description>Known Issues

Installation

Installation on Mac OSX

Please see the page on troubleshooting for Mac.

Simulation

''Function'' gives erroneous values

Functions have been reported to generate erroneous values in the following situation:

	*  Function is defined outside of</description>
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        <description>User Manual

&lt;http://imc.zih.tu-dresden.de/morpheus/Morpheus_User_Manual_v1.1_rev881.pdf&gt;

Download user manual (pdf).

The user manual is the main resource for information on:

	*  graphical user interface and workflow tools
	*  modeling formalisms and numerical implementation
	*  model description language 
	*  model integration and simulation schedule</description>
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        <dc:date>2013-08-01T15:36:00+00:00</dc:date>
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        <description>Model description language

The Morpheus model description language (MDL) is a domain-specific extensible mark-up language (XML) for the specification of multiscale multicellular simulation models. It has been developed to separate the process of modeling from numerical implementation to allow users to specify simulation models in terms of familiar biological and mathematical concepts rather than in a general-purpose programming language (see sections [sub:Domain-specific-language] and [sec:Glos…</description>
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        <title>documentation:performance</title>
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        <description>Performance and scalability

The performance and scalability of simulations in Morpheus heavily depend on the type of (multi-scale) model that is being simulated. It is therefore difficult to make general statements on the computational efficiency. However, we can test the performance on a set of $10^2$$20^2$$50^2$$100^2$$200^2$$500^2$$1000^2$$40^2$$100^2$$200^2$$400^2$$1000^2$</description>
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        <description>Publications

Research papers
 Meyer, K., Ostrenko, O., Bourantas, G., Morales-Navarrete, H., Porat-Shliom, N., Segovia-Miranda, F., Nonaka, H., Ghaemi, A., Verbavatz, J.M., Brusch, L. and Sbalzarini, I., Kalaidzidis, Y., Weigert, R., Zerial M. 
A Predictive 3D Multi-Scale Model of Biliary Fluid Dynamics in the Liver Lobule. Cell Systems</description>
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        <dc:date>2013-08-02T22:02:42+00:00</dc:date>
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        <title>documentation:tech_specs</title>
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        <description>Technical specification

Solvers

Ordinary differential equations (ODE)

Morpheus implements explicit finite different solvers of numerical integration of ODEs:

	*  Euler's method: 1st order
	*  Heun's method (a.k.a. midpoint): 2nd order
	*  Runge-Kutta's method: 4th order

and stochastic differential equations (SDEs):$\delta t$$\boldsymbol{x}$$\sigma$$H=\sum_{\sigma &gt; 0} \lambda_V (v_\sigma - V_t)^2 + \sum_{\sigma &gt; 0} \lambda_P (p_\sigma - P_t)$$v_\sigma$$p_\sigma$$\sigma$$V_t$$P_t$$H$$\lambd…</description>
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        <dc:date>2021-08-18T18:34:46+00:00</dc:date>
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        <description>Work flow tools

Morpheus has a number of nifty tools to optimize your work flow from model development to high performance computing. 

Here, we present some use cases that use these features.

Model development and testing

Copy / paste between models</description>
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