Table of Contents
Module 3: Activator-Inhibitor
Module 3: Activator-Inhibitor
Author: Lutz Brusch
Aim:
Introduce self-organized pattern formation (Turing patterns)
Show the potential of qualitative/theoretical modeling
Description:
Activator-Inhibitor models
Theoretical introduction on Turing patterns (1951)
Self-organized organizer
large system size = periodic pattern
change inhibitor diffusion and observe changing pattern wavelength
half-wavelength system size and no flux bc. = spontaneous symmetry break of homogeneous init.cond. with max and min at opposite boundaries
Fish coat pattern: Miyazawa et al.
Trigger discussion:
Parameters and variables do no longer correspond to molecules anymore
What is the explanatory power of ‘blending model’?
Bottom-up, top-down, middle-out
Paper:
Miyazawa, Okamoto and Kondo, Blending of animal colour patterns by hybridization, Nature Communications, 2010.
link
Morpheus models:
Activator-Inhibitor: reaction-diffusion in one dimension
Turing patterns: spatial parameter exploration