=== Module 3: Activator-Inhibitor === Author: Lutz Brusch Aim: * Introduce self-organized pattern formation (Turing patterns) * Show the potential of qualitative/theoretical modeling Description: * Activator-Inhibitor models * Theoretical introduction on Turing patterns (1951) * Self-organized organizer * large system size = periodic pattern * change inhibitor diffusion and observe changing pattern wavelength * half-wavelength system size and no flux bc. = spontaneous symmetry break of homogeneous init.cond. with max and min at opposite boundaries * Fish coat pattern: Miyazawa et al. * Trigger discussion: * Parameters and variables do no longer correspond to molecules anymore * What is the explanatory power of ‘blending model’? * Bottom-up, top-down, middle-out Paper: * Miyazawa, Okamoto and Kondo, Blending of animal colour patterns by hybridization, Nature Communications, 2010. [[http://www.nature.com/ncomms/journal/v1/n6/full/ncomms1071.html|link]] Morpheus models: * [[examples:miscellaneous#Activator-Inhibitor: reaction-diffusion in one dimension|Activator-Inhibitor: reaction-diffusion in one dimension]] * [[examples:reaction-diffusion#Turing patterns: spatial parameter exploration|Turing patterns: spatial parameter exploration]]